When sending an e-mail in Outlook, don’t bother clicking on that “Send” button — press Ctrl+Enter to send. You’ll need to confirm with a dialog box the first time. The Shortcut Alt-S also works.
Some people complain as they send a vital email by accident before it was ready. Maybe this can be solved by using some built-in features of outlook: You can delay the delivery of an individual e-mail message or you can use rules to delay the delivery of all messages by having them held in the Outbox for a specified time after you click Send. For further details see http://office.microsoft.com/en-us/outlook/HP012328171033.aspx